Per Island Trader's suggestion I used a tube of Six10 epoxy to fill some holes in the transom and was left with these impressions:
1. Excellent product for the task. Nice thickness somewhere between mayo and peanut butter. As reelescape1 mentioned the nozzle tip is less than 1/4" making it very functional.
2. Very easy to use. As Terry said, "no muss, no fuss." And no clean-up.
3. The tube comes with a cap in case you don't use it all, but you'll need a new static mixer nozzle. The run a couple of bucks a piece.
4. The tube does not go very far - only filled 34 holes 1/4" x 1-1/4". Near as I could tell, little less than half the caulk tube is actual product.
5. Very expensive $22 +tax @ West Marine.
All in all, it was quick and clean but I'll need another tube. I think Caymanboy's approach of mixing your own epoxy and spooning into empty caulk tube will save a lot of money. On the other hand if you want to get something done during lunch hour, its pretty convenient.